ABSTRACT
Objective:To explore the effect of repetitive high-frequency magnetic stimulation (H-F rTMS) of the dorsolateral part of the prefrontal cortex (DLPFC) combined with smoking-related cues on nicotine addicts′ cigarette craving, the concentration of exhaled CO and sleep quality.Methods:Sixty nicotine addicts were randomly divided into groups A, B and C, each of 20. All were given H-F rTMS five times a week for two weeks, while those in groups A and B watched smoking and non-smoking pictures for ten minutes, respectively. Before and after the intervention, all of the subjects self-reported their cigarette cravings using a visual analogue scale. Exhaled CO (CO ppm) was measured and the Pittsburgh sleep quality index (PSQI) was evaluated. Results:After the intervention the average craving score, CO ppm and PSQI score had improved significantly in all three groups. The average craving score and CO ppm of group A were both significantly better than in the other two groups. Conclusions:rTMS can significantly improve cigarette craving, CO ppm and sleep quality of cigarette adicts. Viewing smoking-related pictures as an addition to rTMS can even better the effects of rTMS.
ABSTRACT
Objective:To investigate anye effect of magnetic stimulation of the sacral nerve (SMS) on acontractile detrusor disorder.Methods:Thirty spinal cord injury patients with neurogenic bladder dysfunction were randomly divided into a stimulation group and a sham group, each of 15. In a first experiment the stimulation group was treated with SMS (over S3) with a bladder volume of 100ml on the 1st day, 200ml on the 2nd day, and 300ml on the 3rd day. Each SMS session involved a total of 1500 pulses at 15Hz in 10-second bursts with 30-second intervals. For the sham group the treatment was ostensibly identical, but the coil was rotated 90 degrees. Maximum detrusor pressure was assessed before and immediately after each SMS session. In a second experiment the bladder volumes were adjusted to 200-300ml ultrasonically before treatment. Both groups were treated twice a day, 5 days a week for 4 weeks. Maximum detrusor pressures were detected at the bladder volumes of 0ml, 100ml, 200ml and 300ml before and after the 4 weeks of treatment.Results:The stimulation group′s average pressures at 200ml and 300ml had increased significantly immediately after SMS and were then significantly higher than the sham group′s averages. After 4 weeks of treatment the stimulation group′s maximum pressures were significantly higher than before treatment at all of the bladder volumes tested, and were significantly better than those of the sham group.Conclusions:SMS can significantly improve detrusor functioning, but the effect is related to bladder volume.